{"created":"2023-06-20T14:26:51.888600+00:00","id":8257,"links":{},"metadata":{"_buckets":{"deposit":"22436802-0784-4acf-92e1-ff0ef4f803f8"},"_deposit":{"created_by":3,"id":"8257","owners":[3],"pid":{"revision_id":0,"type":"depid","value":"8257"},"status":"published"},"_oai":{"id":"oai:aue.repo.nii.ac.jp:00008257","sets":["6:74:1014"]},"author_link":["356"],"item_3_biblio_info_7":{"attribute_name":"書誌事項","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2022-03-01","bibliographicIssueDateType":"Issued"},"bibliographicPageEnd":"99","bibliographicPageStart":"90","bibliographicVolumeNumber":"71","bibliographic_titles":[{"bibliographic_title":"愛知教育大学研究報告. 自然科学編"}]}]},"item_3_description_27":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"subitem_description":"text","subitem_description_type":"Other"}]},"item_3_description_5":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"Chondroitin sulfate is a group of polysaccharides containing repeating disaccharide units composed of GlcA-GalNAc. Each disaccharide unit bears sulfate groups on the various position of the component sugars: position 4 of GalNAc residues in A unit; position 6 of GalNAc residues in C unit; position 6 of GalNAc residue and position 2 of GlcA residue in D unit; and position 4 and 6 of GalNAc residue in E unit. Specific sulfotransferases are involved in the synthesis of these sulfate groups. Of these sulfotransferases, GalNAc 4-sulfate 6-O-sulfotransferase (GalNAc4S-6ST) and uronyl 2-O-sulfotransferase (2OST) are responsible for the formation of E unit and D unit, respectively. Both GalNAc4S-6ST and 2OST recognize not only the kind and position of the sugar residues but also sulfation pattern around the targeted sugar residues. GalNAc4S-6ST efficiently transfers sulfate to position 6 of GalNAc(4-SO_4) residue in a nonreducing terminal sequence, GalNAc(4-SO_4)-GlcA(2-SO_4)-GalNAc(6-SO_4) in addition to position 6 of GalNAc(4-SO_4) residue in the repeating disaccharides units. On the other hand, 2OST preferentially transfers sulfate to position 2 of GlcA residue in a sequence, GalNAc(4-SO_4)-GlcA-GalNAc(6-SO_4). A highly sulfated nonreducing terminal sequence, GalNAc(4, 6-SO_4)-GlcA(2-SO_4)-GalNAc(6-SO_4) appears to be produced by the concerted action of these sulfotransferases.","subitem_description_type":"Abstract"}]},"item_3_publisher_8":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":" 愛知教育大学"}]},"item_3_source_id_11":{"attribute_name":"書誌レコードID","attribute_value_mlt":[{"subitem_source_identifier":"AA12466167","subitem_source_identifier_type":"NCID"}]},"item_3_source_id_9":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"1884-5169","subitem_source_identifier_type":"ISSN"}]},"item_3_text_10":{"attribute_name":"書誌情報","attribute_value_mlt":[{"subitem_text_value":"愛知教育大学研究報告, 自然科学編. 2022, 71, p. 90-99. "}]},"item_3_text_26":{"attribute_name":"著者別名","attribute_value_mlt":[{"subitem_text_value":"科研費研究者番号,90024067"}]},"item_3_text_4":{"attribute_name":"著者(別言語)","attribute_value_mlt":[{"subitem_text_value":"羽渕, 脩躬"}]},"item_3_version_type_14":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"Habuchi, Osami"}],"nameIdentifiers":[{"nameIdentifier":"356","nameIdentifierScheme":"WEKO"},{"nameIdentifier":"90024067","nameIdentifierScheme":"e-Rad","nameIdentifierURI":"https://kaken.nii.ac.jp/ja/search/?qm=90024067"},{"nameIdentifier":"90024067","nameIdentifierScheme":"KAKEN - 研究者検索","nameIdentifierURI":"https://nrid.nii.ac.jp/ja/nrid/1000090024067/"}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2022-03-29"}],"displaytype":"detail","filename":"kenshi719099.pdf","filesize":[{"value":"797.2 kB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"kenshi719099.pdf","url":"https://aue.repo.nii.ac.jp/record/8257/files/kenshi719099.pdf"},"version_id":"1ab8f384-9670-4753-b68a-e538fa06419c"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"departmental bulletin paper","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"Formation of a Highly Sulfated Nonreducing Terminal Sequence in Chondroitin Sulfate by Concerted Reactions of GalNAc 4-Sulfate 6-O-Sufotransferase and Uronyl 2-O-Sulfotransferase","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"Formation of a Highly Sulfated Nonreducing Terminal Sequence in Chondroitin Sulfate by Concerted Reactions of GalNAc 4-Sulfate 6-O-Sufotransferase and Uronyl 2-O-Sulfotransferase","subitem_title_language":"en"}]},"item_type_id":"3","owner":"3","path":["1014"],"pubdate":{"attribute_name":"公開日","attribute_value":"2022-03-29"},"publish_date":"2022-03-29","publish_status":"0","recid":"8257","relation_version_is_last":true,"title":["Formation of a Highly Sulfated Nonreducing Terminal Sequence in Chondroitin Sulfate by Concerted Reactions of GalNAc 4-Sulfate 6-O-Sufotransferase and Uronyl 2-O-Sulfotransferase"],"weko_creator_id":"3","weko_shared_id":-1},"updated":"2023-06-20T15:22:00.050490+00:00"}