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損傷回復過程における筋節構造の変化
http://hdl.handle.net/10424/00008308
http://hdl.handle.net/10424/00008308d65731a0-b180-4642-ae66-a4723e018af3
名前 / ファイル | ライセンス | アクション |
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Item type | 紀要論文 / Departmental Bulletin Paper(1) | |||||
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公開日 | 2019-04-10 | |||||
タイトル | ||||||
タイトル | 損傷回復過程における筋節構造の変化 | |||||
言語 | ||||||
言語 | jpn | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | muscle | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | crush injury | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | sarcomere structure | |||||
資源タイプ | ||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
資源タイプ | departmental bulletin paper | |||||
その他のタイトル | ||||||
その他のタイトル | Sarcomere Structural Change in Muscle Regeneration After Crush Injury | |||||
著者 |
犬塚, 貴久
× 犬塚, 貴久× 中山, 聖× 吉川, 侑希× 春日, 規克 |
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研究者総覧へのリンク | ||||||
春日, 規克 | ||||||
http://souran.aichi-edu.ac.jp/souran/profile.do?id=42JOT20W&lng=ja | ||||||
著者(別言語) | ||||||
Inuzuka, Takahisa | ||||||
著者(別言語) | ||||||
Nakayama, Hijiri | ||||||
著者(別言語) | ||||||
Yoshikawa, Yuki | ||||||
著者(別言語) | ||||||
Kasuga, Norikatsu | ||||||
抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | Exercise of a living body is expressed by shrinkage with the sarcomere as a minimum unit. Many studies report decay of sarcomere structure due to exercise, but few studies focused on regeneration. Therefore, in this study, the recovery change of the sarcomeric microstructure of the injury skeletal muscle was examined. The Fischer 344 rats were anesthetized and muscle of extensor digitorum longus was exposed. The muscle was crushed by strongly compressing with tip of the tweezers for 5 seconds. The crush site was the muscle central portion or muscle edge portion. Regeneration of the sarcomere structure was examined at 3, 7, 15 and 60 days after crush. 16-μm longitudinal sections of frozen dissected muscle were performed immunohistochemical staining with monoclonal antibodies of development MHC (dMHC) and α-actinin, and observed the sarcomere structure at the muscle center, muscle edge portions, and the mid portion between center and edge. The expression of dMHC was confirmed in crushed portions 3 to 15 days after injury. The maximum tetanic tension showed the lowest value 3 days after the crush injury, and thereafter the recovery was observed. We found that the expression of dMHC was confirmed in damaged areas 3 to 15 days after injury. The exercise tension showed the lowest value 3 days after the crush injury, and thereafter the recovery was observed. At 7-15 days after injury, the sarcomere length of the crushed portion was significantly higher than that of the control muscle and was significantly lower at the number of sarcomere per 100mm. These disorder were thought to be related to functional recovery such as maximum tension, and were not observed in the muscle 60 days after injury. | |||||
書誌事項 |
愛知教育大学研究報告. 芸術・保健体育・家政・技術科学・創作編 巻 68, p. 31-37, 発行日 2019-03-01 |
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出版者 | ||||||
出版者 | 愛知教育大学 | |||||
ISSN | ||||||
収録物識別子タイプ | ISSN | |||||
収録物識別子 | 1884-5150 | |||||
書誌情報 | ||||||
愛知教育大学研究報告. 芸術・保健体育・家政・技術科学・創作編. 2019, 68, p. 31-37. | ||||||
書誌レコードID | ||||||
収録物識別子タイプ | NCID | |||||
収録物識別子 | AA12466178 | |||||
著者版フラグ | ||||||
出版タイプ | VoR | |||||
出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 | |||||
著者別名 | ||||||
イヌズカ, タカヒサ | ||||||
著者別名 | ||||||
ナカヤマ, ヒジリ | ||||||
著者別名 | ||||||
ヨシカワ, ユキ | ||||||
著者別名 | ||||||
カスガ, ノリカツ | ||||||
資源タイプ | ||||||
内容記述タイプ | Other | |||||
内容記述 | text |